DrugindexOnline^{2nd edition}

Generic name: Flutamide
Brand names: Eulexin

Why is Eulexin prescribed?

Eulexin is used along with drugs such as Lupron to treat prostate cancer. Eulexin belongs to a class of drugs known as antiandrogens. It blocks the effect of the male hormone testosterone. Giving Eulexin with Lupron, which reduces the body's testosterone levels, is one way of treating prostate cancer. For some forms of prostate cancer, radiation therapy is given along with the drugs.

Most important fact about Eulexin

Taking Eulexin and Lupron together is essential in this form of treatment. You should not interrupt their doses or stop taking either of these medications without consulting your doctor.

How should you take Eulexin?

Take Eulexin exactly as prescribed. Do not use more or less, and do not take it more often than instructed.

If you develop diarrhea<96>a relatively common side effect of therapy<96>you may find the following measures helpful: drink plenty of fluids; avoid dairy products; increase your intake of whole grains, fruits, and vegetables; avoid laxatives; and take nonprescription antidiarrhea medicine. If the diarrhea continues or becomes severe, contact your doctor.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor immediately. Since Eulexin is always given with another antiandrogen drug, when a side effect develops, it is difficult to know which drug is responsible. Only your doctor can determine if it is safe for you to continue taking Eulexin.

• More common side effects may include:
  Breast tissue swelling and tenderness, diarrhea, hot flashes, impotence, loss of sex drive, nausea, vomiting

When the drugs are used along with radiation therapy, additional side effects may include bladder inflammation, bleeding from the rectum, blood in the urine, and intestinal problems.

Why should Eulexin not be prescribed?

This drug is not intended for women, and should not be used by anyone with serious liver disease. You'll also be unable to take it if it gives you an allergic reaction.

Special warnings about Eulexin

Eulexin has been known to cause liver failure in some patients, in rare cases leading to death. Your doctor will do blood tests to check your liver function before you start treatment with Eulexin, and at regular intervals thereafter. If a liver problem does develop, you may need to take less Eulexin or stop taking the drug altogether. Report any signs or symptoms that might suggest liver damage to your doctor right away. Warning signs include dark urine, itching, flu-like symptoms, jaundice (a yellowing of the skin and eyes), persistent appetite loss, and persistent tenderness on the right side of the upper abdomen.

Possible food and drug interactions when taking Eulexin

If you are already taking the anticoagulant drug warfarin (Coumadin), you will need to be monitored especially closely after treatment with Eulexin begins. Your doctor may need to lower your dosage of warfarin.

Special information if you are pregnant or breastfeeding

Eulexin can harm a developing baby. Women should never take Eulexin, either during pregnancy or at any other time.

Recommended dosage

The recommended adult Eulexin dosage is 2 capsules 3 times a day at 8-hour intervals for a total daily dosage of 750 milligrams.

Overdosage

You may notice breast development or tenderness with an overdose of Eulexin. Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.