DrugindexOnline^{2nd edition}

Generic Name: Sulfacetamide Cream and Gel (sul-fa-SEE-ta-mide)
Brand Name: Ovace

Ovace Cream is used for:

Treating bacterial infections of the skin, including dandruff. It may also be used for other conditions as determined by your doctor.

Ovace Cream is a sulfonamide. It works by restricting the production of folic acid, which bacteria need for growth. This kills the bacteria.

Do NOT use Ovace Cream if:

• you are allergic to any ingredient in Ovace Cream
• you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
• you are taking methenamine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ovace Cream:

Some medical conditions may interact with Ovace Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Ovace Cream. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Silver-containing products (eg, silver sulfadiazine) because they may decrease Ovace Cream's effectiveness
• Methenamine because it may increase the risk of this medicine's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ovace Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ovace Cream:

Use Ovace Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Ovace Cream is for use on the skin only. Ovace Cream may stain clothing and the skin if too much is used. If your skin becomes too dry, apply less to the area.
• To clear up your infection completely, use Ovace Cream for the full course of treatment. Keep using it even if you feel better in a few days.
• Ovace Cream works best if it is used at the same time each day.
• Continue to use Ovace Cream even if you feel well. Do not miss any doses.
• If you miss a dose of Ovace Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ovace Cream.

Important safety information:

• It may take several days for Ovace Cream to work fully.
• Avoid getting Ovace Cream in your eyes, nose, or mouth.
• Talk with your doctor before you use any other medicines or cleansers on your skin.
• Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
• Ovace Cream only works against bacteria; it does not treat viral infections.
• Be sure to use Ovace Cream for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
• Long-term or repeated use of Ovace Cream may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
• Ovace Cream should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ovace Cream while you are pregnant. It is not known if Ovace Cream is found in breast milk after topical use. If you are or will be breast-feeding while you use Ovace Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ovace Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Irritation, stinging, or burning of the skin.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; fever; joint pain; red, swollen, or blistered skin; severe diarrhea; sores in the mouth; stomach cramps/pain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Ovace Cream may be harmful if swallowed. Symptoms of ingestion may include change in the amount of urine; nausea; vomiting.

Proper storage of Ovace Cream:

Store Ovace Cream at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not freeze. Keep Ovace Cream out of the reach of children and away from pets.

General information:

• If you have any questions about Ovace Cream, please talk with your doctor, pharmacist, or other health care provider.
• Ovace Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ovace Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.