Drugs List: Olopatadine Hydrochloride, How to use Olopatadine Hydrochloride

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All about: Olopatadine Hydrochloride

Pronouncation: (oh-low-pat-AD-een HIGH-droe-KLOR-ide)
Class: Ophthalmic antihistamine

Trade Names:
Patanol
- Solution 0.1%

Mechanism of Action

Pharmacology

Inhibits release of histamine from mast cells and relatively selective histamine H1 antagonist. Inhibits type 1 immediate hypersensitivity reactions.

Indications and Usage

Temporary relief of itching caused by allergic conjunctivitis.

Contraindications

Standard considerations.

Dosage and Administration

Adults and Children

1 to 2 drops in affected eye(s) twice daily, 6 to 8 hr apart. If using other topical ophthalmic drugs, separate each medication by 5 min or more.

Storage/Stability

Store between 39° and 86°F. Keep bottle tightly closed.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Ophthalmic

Burning, dry eye, foreign body sensation, hyperemia, keratitis, lid edema, pruritus, stinging.

Miscellaneous

Asthenia, cold syndrome, dysgeusia, headache, pharyngitis, rhinitis, sinusitis.

Precautions

Pregnancy

Category C .

Lactation

Secreted into animal breast milk.

Children

Safety and effectiveness younger than 3 yr of age are not established. Do not instill while wearing contact lenses.

Patient Information

Explain name, dose, action, and potential side effects of drug.
Advise patient that usual dose is 1 drop in affected eye(s) bid at an interval of 6 to 8 hr.
Teach patient proper technique for instilling eye drops: Wash hands; do not allow dropper to touch eye; tilt head back, look up; pull lower eyelid down; instill prescribed number of drops; close eye for 1 to 2 min and apply gentle pressure to bridge of nose; do not rub eye.
Advise patients who wear contact lenses to remove their lenses before instilling this medicine and to wait at least 10 min after instilling eye drop before inserting their lenses. Also, caution these patients to not wear their lenses if the eye is red.
Advise patient that if more than 1 topical ophthalmic drug is being used, administer the drugs at least 5 min apart.
Advise patient to inform health care provider if experiencing side effects or if eye symptoms do not improve or worsen.

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