DrugindexOnline^{2nd edition}

Generic Name: Paromomycin (par-oh-moe-MYE-sin)
Brand Name: Humatin

Humatin is used for:

Treating amoeba infection in the intestines. It is also used in combination with other medicines to manage a serious complication of liver disease (hepatic coma). It may be used for other conditions as determined by your doctor.

Humatin is an antibacterial agent. It works by killing sensitive bacteria.

Do NOT use Humatin if:

• you are allergic to any ingredient in Humatin
• you have a blockage in your intestines

Contact your doctor or health care provider right away if any of these apply to you.

Before using Humatin :

Some medical conditions may interact with Humatin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have hearing problems, bowel problems (eg, ulcers, lesions), myasthenia gravis, Parkinson disease, or kidney problems, or you are dehydrated

Some MEDICINES MAY INTERACT with Humatin . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Digoxin because the actions and side effects may be increased or effectiveness may be decreased by Humatin
• Nondepolarizing muscle relaxants, (eg, pancuronium) or succinylcholine because the actions and side effects may be increased by Humatin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Humatin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Humatin :

Use Humatin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Humatin with food.
• To clear up your infection completely, continue using Humatin for the full course of treatment even if you feel better in a few days. Do not miss any doses.
• If you miss a dose of Humatin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Humatin .

Important safety information:

• It is important to use Humatin for the full course of treatment. Failure to do so may decrease the effectiveness of Humatin .
• Long-term or repeated use of Humatin may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Humatin .
• Use Humatin with extreme caution in INFANTS. Safety and effectiveness have not been confirmed.
• Use Humatin with extreme caution in CHILDREN younger than 10 years of age who have diarrhea or a stomach or bowel infection.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Humatin , discuss with your doctor the benefits and risks of using Humatin during pregnancy. It is unknown if Humatin is excreted in breast milk. If you are or will be breast-feeding while you are using Humatin , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Humatin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea; stomach cramps.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include decreased urination; hearing loss; ringing in the ears; skin tingling or numbness.

Proper storage of Humatin :

Store Humatin between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Humatin out of the reach of children and away from pets.

General information:

• If you have any questions about Humatin , please talk with your doctor, pharmacist, or other health care provider.
• Humatin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Humatin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.